Larsen F, Pehrsson S K, Hammar N, Sköld C M, Izumi T, Nagai S, Shigematsu M, Eklund A
Department of Clinical Physiology and Radiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Sarcoidosis Vasc Diffuse Lung Dis. 2001 Oct;18(3):284-8.
ECG abnormalities are more common in patients with sarcoidosis than in controls. The incidence of cardiac sarcoid granulomas in the Japanese population has been found to be higher than that seen in Caucasians. We compared the prevalence of ECG abnormalities in Japanese and Swedish patients with sarcoidosis.
Twelve-lead routine ECG's were compared between consecutive patients (134 Japanese and 149 Swedish) of similar age with histologically verified sarcoidosis or a high clinical probability of the disease and a history of no more than 12 months before the ECG.
There was no statistically significant difference in the prevalence of first degree AV block, ST-T-segment abnormalities, right bundle branch block (RBBB) and left anterior block (LAH) in Japanese and Swedish patients. Among the Swedes, the results were compared with those of a smaller group (n = 29) of older patients with a longer disease course. In these few patients LAH and RBBB occurred more frequently than in patients with a recent diagnosis.
ECG abnormalities in patients with sarcoidosis seem to be of similar frequency in Japan and Sweden. ST-T changes and first degree AV block would appear early in the course of the disease, whereas more pronounced conduction defects may appear later.
结节病患者的心电图异常比对照组更为常见。已发现日本人群中心脏结节病肉芽肿的发生率高于白种人。我们比较了日本和瑞典结节病患者心电图异常的患病率。
对年龄相仿、经组织学证实患有结节病或临床高度疑似该病且在心电图检查前病程不超过12个月的连续患者（134名日本患者和149名瑞典患者）的十二导联常规心电图进行比较。
日本和瑞典患者一度房室传导阻滞、ST-T段异常、右束支传导阻滞（RBBB）和左前分支阻滞（LAH）的患病率无统计学显著差异。在瑞典人中，将结果与病程较长的较小老年患者组（n = 29）进行了比较。在这少数患者中，LAH和RBBB的发生率高于近期诊断的患者。
日本和瑞典结节病患者的心电图异常发生率似乎相似。ST-T改变和一度房室传导阻滞可能在疾病早期出现，而更明显的传导缺陷可能在后期出现。
