Kramer R E, Sokol R J, Yerushalmi B, Liu E, MacKenzie T, Hoffenberg E J, Narkewicz M R
Pediatric Liver Center and Liver Transplantation Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Children's Hospital and University of Colorado Health Sciences Center, Denver, Colorado 80218, USA.
J Pediatr Gastroenterol Nutr. 2001 Sep;33(3):245-9. doi: 10.1097/00005176-200109000-00003.
Large-volume paracentesis has been evaluated for both therapeutic and diagnostic purposes in the management of ascites in cirrhotic adults. There are no published data relating to the safety, efficacy, or methods of this procedure in children. The objective of this study was to characterize the authors' initial experience with large-volume paracentesis (> 50 ml/kg of ascites) for removal of tense abdominal ascites in the pediatric population.
Retrospective chart review was performed of 21 large-volume paracentesis sessions in seven children (ages 6 months-18 years) with tense ascites that did not respond to other measures.
Mean volume removed was 3,129 +/- 2,966 ml (mean +/- standard deviation) or 118 +/- 56 ml/kg over 2.9 +/- 3.7 hours by a 16-gauge intravascular catheter in 6 sessions, by an 18-gauge intravascular catheter in three sessions, and by a 15-gauge fenestrated, stainless-steel paracentesis needle in 12 sessions. Large-volume paracenteses performed with the paracentesis needle had significantly shorter duration of drainage and faster flow rates than those performed with the intravascular catheter. The only complication encountered was decreased urine output in one session.
Large-volume paracentesis is a safe and effective therapeutic method for managing tense abdominal ascites in children. The use of the paracentesis needle significantly improved the speed and efficiency of large-volume paracentesis compared with the intravascular catheter.
在肝硬化成人腹水的管理中,已对大量腹腔穿刺术的治疗和诊断目的进行了评估。目前尚无关于该操作在儿童中的安全性、有效性或方法的已发表数据。本研究的目的是描述作者在儿科人群中使用大量腹腔穿刺术(>50 ml/kg腹水)清除紧张性腹水的初步经验。
对7名(年龄6个月至18岁)患有紧张性腹水且对其他措施无反应的儿童进行的21次大量腹腔穿刺术进行回顾性病历审查。
在6次操作中使用16号血管内导管、3次操作中使用18号血管内导管、12次操作中使用15号带孔不锈钢腹腔穿刺针,在2.9±3.7小时内平均抽出量为3129±2966 ml(平均值±标准差)或118±56 ml/kg。使用腹腔穿刺针进行的大量腹腔穿刺术的引流时间明显短于使用血管内导管进行的操作,流速也更快。唯一遇到的并发症是一次操作中尿量减少。
大量腹腔穿刺术是治疗儿童紧张性腹水的一种安全有效的治疗方法。与血管内导管相比,使用腹腔穿刺针显著提高了大量腹腔穿刺术的速度和效率。