Pediatric Gastroenterology, Hepatology and Nutrition, Deprtment of Pediatrics, University of California, San Francisco, CA 93638, United States.
World J Gastroenterol. 2012 Mar 21;18(11):1176-84. doi: 10.3748/wjg.v18.i11.1176.
Portal hypertension can be caused by a wide variety of conditions. It frequently presents with bleeding from esophageal varices. The approach to acute variceal hemorrhage in children is a stepwise progression from least invasive to most invasive. Management of acute variceal bleeding is straightforward. But data on primary prophylaxis and long term management prevention of recurrent variceal bleeding in children is scarce, therefore prospective multicenter trials are needed to establish best practices.
门静脉高压症可由多种疾病引起。其常表现为食管静脉曲张破裂出血。儿童急性静脉曲张出血的治疗方法是从微创到最具侵袭性的逐步进展。急性静脉曲张出血的治疗相对简单。但儿童一级预防和长期管理(预防静脉曲张再出血)的数据很少,因此需要开展前瞻性多中心试验来制定最佳实践。