Cox D, Clarke W, Gonder-Frederick L, Kovatchev B
University of Virginia, Charlottesville, Virginia, USA.
Int J Clin Pract Suppl. 2001 Sep(123):38-42.
Driving is a complex, multi-task activity that can be affected by cognitive impairment resulting from episodes of severe hypoglycaemia. Intensive insulin therapy increases the likelihood of severe hypoglycaemia but there have been few studies examining effects on driving skills. A survey carried out recently indicated that patients with type 1 diabetes had twice the incidence of driving accidents than their non-diabetic spouses or patients with type 2 diabetes. The motor accidents were associated with more frequent low blood glucose while driving and less frequent self-monitoring. In driving simulation tests it was found that driving has an intrinsic metabolic demand that can contribute to hypoglycaemia. Driving performance began to deteriorate at around 3.6 mmol/l but drivers frequently did not recognise and failed to treat the hypoglycaemia. Those who did self-treat had more driving relevant symptoms and less neuroglycopenia quantified by EEG alpha-theta differences. Patients should be recommended not to begin driving if blood glucose is below 4.5 mmol/l and should not continue to drive if they suspect that blood glucose has fallen below 4 mmol/l while driving. If hypoglycaemia is suspected patients should immediately pull off the road, measure blood glucose if possible, treat themselves as necessary and not resume driving until glucose and cognitive-motor function return to normal. The problems of driving and hypoglycaemia should be discussed with patients with diabetes and behavioural interventions instigated. To this end, Blood Glucose Awareness Training (BGAT) and Hypoglycaemia Anticipation, Awareness and Treatment Training (HAATT) have been developed and shown to markedly reduce incidence of driving mishaps.
驾驶是一项复杂的多任务活动,可能会受到严重低血糖发作导致的认知障碍影响。强化胰岛素治疗会增加严重低血糖的可能性,但很少有研究考察其对驾驶技能的影响。最近开展的一项调查表明,1型糖尿病患者发生交通事故的几率是其非糖尿病配偶或2型糖尿病患者的两倍。这些交通事故与驾驶时更频繁的低血糖以及较少的自我监测有关。在驾驶模拟测试中发现,驾驶本身存在代谢需求,这可能导致低血糖。当血糖浓度约为3.6毫摩尔/升时,驾驶表现开始变差,但驾驶员往往没有意识到低血糖,也未能进行治疗。那些进行自我治疗的人有更多与驾驶相关的症状,且通过脑电图α波-θ波差异量化的脑缺糖情况较少。应建议患者在血糖低于4.5毫摩尔/升时不要开始驾驶,如果怀疑驾驶时血糖已降至4毫摩尔/升以下,则不应继续驾驶。如果怀疑发生低血糖,患者应立即靠边停车,尽可能测量血糖,必要时进行自我治疗,直到血糖和认知运动功能恢复正常后再继续驾驶。应与糖尿病患者讨论驾驶和低血糖问题,并采取行为干预措施。为此,已经开发了血糖意识培训(BGAT)和低血糖预期、意识与治疗培训(HAATT),并已证明可显著降低驾驶事故的发生率。