Benitez R M, Vogel R A
Department of Medicine, University of Maryland School of Medicine, Baltimore 21201, USA.
Clin Cardiol. 2001 Oct;24(10):642-50. doi: 10.1002/clc.4960241003.
Conventional cardiac risk factors do not fully explain the incidence of coronary artery disease and coronary events. Risk stratification and therapy based solely on these conventional risk factors may exclude a population who would otherwise benefit from lifestyle and risk factor modification. Recent efforts to improve our ability to recognize individuals and populations at increased risk of coronary events have focused on the noninvasive imaging of atherosclerosis, both in coronary and extracoronary arterial beds, or the identification of "non-traditional" serum markers. We review the complimentary role of these newer methods of risk stratification in the context of conventional risk factor evaluation.
传统的心脏危险因素并不能完全解释冠状动脉疾病和冠状动脉事件的发生率。仅基于这些传统危险因素进行风险分层和治疗,可能会将那些原本可从生活方式和危险因素改善中获益的人群排除在外。最近,为提高我们识别冠状动脉事件风险增加的个体和人群的能力所做的努力,集中在对冠状动脉和冠状动脉外动脉床的动脉粥样硬化进行无创成像,或识别“非传统”血清标志物。我们在传统危险因素评估的背景下,综述这些较新的风险分层方法的补充作用。