Isaäcson M
Department of Clinical Microbiology and Infectious Diseases, South African Institute for Medical Research, Johannesburg, South Africa.
Clin Infect Dis. 2001 Nov 15;33(10):1707-12. doi: 10.1086/322620. Epub 2001 Oct 10.
This short review covers 6 viral hemorrhagic fevers (VHFs) that are known to occur in Africa: yellow fever, Rift Valley fever, Crimean-Congo hemorrhagic fever, Lassa fever, Marburg virus disease, and Ebola hemorrhagic fever. All of these have at one time or another affected travelers, often the adventurous kind who are "roughing it" in rural areas, who should therefore be made aware by their physicians or travel health clinics about their potential risk of exposure to any VHF along their travel route and how to minimize the risk. A significant proportion of VHF cases involving travelers have affected expatriate health care workers who were nosocomially exposed in African hospitals or clinics. The VHFs are associated with a high case-fatality rate but are readily prevented by well-known basic precautions.
本简短综述涵盖了已知在非洲发生的6种病毒性出血热(VHF):黄热病、裂谷热、克里米亚-刚果出血热、拉沙热、马尔堡病毒病和埃博拉出血热。所有这些疾病都曾在不同时期影响过旅行者,这些旅行者往往是那些在农村地区“艰苦旅行”的冒险型人群,因此医生或旅行健康诊所应让他们了解在旅行途中接触任何VHF的潜在风险以及如何将风险降至最低。相当一部分涉及旅行者的VHF病例影响了在非洲医院或诊所因医院感染而接触病毒的外籍医护人员。VHF的病死率很高,但通过众所周知的基本预防措施很容易预防。