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[支气管肺泡灌洗术在马下呼吸道疾病诊断中的应用]

[Bronchoaveolar lavage for the diagnosis of lower airway disorders in horses].

作者信息

Laan T T, van Nieuwstadt R A, Sloet van Oldruitenborgh-Oosterbaan M M, Breukink H J

机构信息

Hoofdafdeling Gezondheidszorg Paard, Discipline Inwendige Ziekte, Faculteit der Diergeneeskunde, Yalelaan 12-16, 3584 CM Utrecht.

出版信息

Tijdschr Diergeneeskd. 2001 Sep 1;126(17):554-9.

Abstract

Equine pulmonary disease and especially the terminology of lower airway disease have been subject to discussion. Besides established terms such as 'Chronic Obstructive Pulmonary Disease' (COPD) and Chronic bronchitis, the term 'small airway disease' (SAD) has been introduced, for respiratory disease with inflammation in the lower airways in combination with exercise intolerance. Bronchoalveolar lavage (BAL) enables the practitioner to diagnose SAD in an early stage when there are no other signs such as coughing or exudate in the trachea. The BAL fluid is microscopically examined after centrifugation. BAL cytology, especially neutrophilia, eosinophilia, and an increase in mast cells, is important, not only to decide whether SAD is present but also to determine in the choice of therapy.

摘要

马肺部疾病,尤其是下气道疾病的术语一直存在争议。除了已有的术语如“慢性阻塞性肺疾病”(COPD)和慢性支气管炎外,“小气道疾病”(SAD)这一术语也被引入,用于描述伴有运动不耐受的下气道炎症性呼吸道疾病。支气管肺泡灌洗(BAL)使从业者能够在早期诊断SAD,此时尚无咳嗽或气管渗出物等其他症状。灌洗后的液体经离心后进行显微镜检查。BAL细胞学检查,尤其是中性粒细胞增多、嗜酸性粒细胞增多和肥大细胞增多,不仅对于确定是否存在SAD很重要,而且对于确定治疗方案的选择也很重要。

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