Seidler A, Bolm-Audorff U, Heiskel H, Henkel N, Roth-Küver B, Kaiser U, Bickeböller R, Willingstorfer W J, Beck W, Elsner G
Institute of Occupational Medicine, Johann Wolfgang Goethe-University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
Occup Environ Med. 2001 Nov;58(11):735-46. doi: 10.1136/oem.58.11.735.
To investigate the relation with a case-control study between symptomatic osteochondrosis or spondylosis of the lumbar spine and cumulative occupational exposure to lifting or carrying and to working postures with extreme forward bending.
From two practices and four clinics were recruited 229 male patients with radiographically confirmed osteochondrosis or spondylosis of the lumbar spine associated with chronic complaints. Of these 135 had additionally had acute lumbar disc herniation. A total of 197 control subjects was recruited: 107 subjects with anamnestic exclusion of lumbar spine disease were drawn as a random population control group and 90 patients admitted to hospital for urolithiasis who had no osteochondrosis or spondylosis of the lumbar spine radiographically were recruited as a hospital based control group. Data were gathered in a structured personal interview and analysed using logistic regression to control for age, region, nationality, and other diseases affecting the lumbar spine. To calculate cumulative forces to the lumbar spine over the entire working life, the Mainz-Dortmund dose model (MDD), which is based on an overproportional weighting of the lumbar disc compression force relative to the respective duration of the lifting process was applied with modifications: any objects weighing >or=5 kg were included in the calculation and no minimum daily exposure limits were established. Calculation of forces to the lumbar spine was based on self reported estimates of occupational lifting, trunk flexion, and duration.
For a lumbar spine dose >9 x 10(6) Nh (Newton x hours), the risk of having radiographically confirmed osteochondrosis or spondylosis of the lumbar spine as measured by the odds ratio (OR) was 8.5 (95% confidence interval (95% CI) 4.1 to 17.5) compared with subjects with a load of 0 Nh. To avoid differential bias, forces to the lumbar spine were also calculated on the basis of an internal job exposure matrix based on the control subjects' exposure assessments for their respective job groups. Although ORs were lower with this approach, they remained significant.
The calculation of the sum of forces to the lumbar spine is a useful tool for risk assessment for symptomatic osteochondrosis or spondylosis of the lumbar spine. The results suggest that cumulative occupational exposure to lifting or carrying and extreme forward bending increases the risk for developing symptomatic osteochondrosis or spondylosis of the lumbar spine.
通过病例对照研究,调查腰椎症状性骨软骨病或脊椎病与累积职业性提举或搬运暴露以及极端前屈工作姿势之间的关系。
从两家诊所和四家门诊部招募了229名经影像学确诊患有与慢性主诉相关的腰椎骨软骨病或脊椎病的男性患者。其中135人还患有急性腰椎间盘突出症。共招募了197名对照受试者:107名经回忆排除腰椎疾病的受试者作为随机人群对照组,90名因尿石症入院且经影像学检查无腰椎骨软骨病或脊椎病的患者作为医院对照组。通过结构化个人访谈收集数据,并使用逻辑回归分析以控制年龄、地区、国籍和其他影响腰椎的疾病。为了计算整个工作生涯中腰椎所承受的累积力,应用了美因茨-多特蒙德剂量模型(MDD),该模型基于相对于提举过程各自持续时间的椎间盘压缩力的超比例加权,并进行了修改:计算中纳入了任何重量≥5千克的物体,且未设定每日最低暴露限值。腰椎受力的计算基于自我报告的职业提举、躯干屈曲和持续时间估计值。
对于腰椎剂量>9×10⁶ Nh(牛顿×小时),与负荷为0 Nh的受试者相比,经比值比(OR)测量的影像学确诊腰椎骨软骨病或脊椎病的风险为8.5(95%置信区间(95% CI)4.1至17.5)。为避免差异偏倚,还根据基于对照受试者各自工作组暴露评估的内部工作暴露矩阵计算腰椎受力。尽管采用这种方法时OR值较低,但仍具有显著性。
腰椎受力总和的计算是腰椎症状性骨软骨病或脊椎病风险评估的有用工具。结果表明,累积职业性提举或搬运暴露以及极端前屈会增加患腰椎症状性骨软骨病或脊椎病的风险。