[Multivariate analysis of clinical factors in restenosis after coronary interventional treatment].

OBJECTIVE

To found the independent predictors for restenosis after coronary interventional treatment.

METHODS

Quantitative angiography was performed in 103 patients(128 successfully dilated lesions) at angioplasty and at 6-month follow-up, and then univariate analysis and multivariate logistic regression analysis were performed to identify correlates of restenosis with clinical factors.

RESULTS

The total restenosis rate was 39.8% (51 of 128 lesions). According to univariate analysis, the patients who had undergone coronary tenting > or = 3.5 mm had a lower rate of restenosis(3/29 and 6/30) and the others with the ACC/AHA lesion type B and C(46/51 and 51/77), collateral circulation to the obstruction set(17/51 and 2/77), high percentage diameter stenosis before PTCA(86 +/- 14)% and (79 +/- 15)%, and high maximal inflation pressure(8.3 +/- 2.1) kPa and (7.4 +/- 1.7) kPa had a higher rate of restenosis (P < 0.01). Stable angina showed a low restenosis rate (3/29 and 6/30). The less minimal lumen diameter before(0.43 +/- 0.41) mm and (0.66 +/- 0.43) mm and after PTCA(2.56 +/- 0.55) mm and (2.85 +/- 0.59) mm, had the higher the restenosis rate (P < 0.05). Multivariate logistic regression analysis showed that coronary stenting had a low rate of restenosis, and that lesion type B and C, high percentage diameter stenosis before PTCA, high maximal inflation pressure, and male had a high rate of restenosis.

CONCLUSION

Coronary stent, percentage diameter stenosis before PTCA, lesion type, maximal inflation pressure, and sex were independent predictors for restenosis.