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[病毒与宫颈癌]

[Viruses and cervical cancers].

作者信息

Mathevet P

机构信息

Service de Gynécologie-Obstétrique Hôpital Edouard-Herriot 69437 Lyon.

出版信息

Rev Prat. 2001 Sep 1;51(13):1413-6.

Abstract

Currently it is evident that human papillomaviruses are involved in the development of cervical cancer. The mechanisms of cancer initiation are in relation with certain types of papillomavirus. But the discrepancy between the high prevalence of papillomavirus infection and the low frequency of cancer in infected women, gives evidence of the importance of healing process in relation with the host's immune response and the activation of other carcinogenic factors. The understanding of the role of papillomavirus in cervical cancer, gives prospects to prophylactic and therapeutic strategies in relation with antiviral treatments or papillomavirus-specific vaccines.

摘要

目前很明显,人乳头瘤病毒与宫颈癌的发生有关。癌症起始机制与某些类型的乳头瘤病毒有关。但是,乳头瘤病毒感染的高发生率与受感染女性中癌症的低发生率之间的差异,证明了与宿主免疫反应及其他致癌因素激活相关的愈合过程的重要性。对乳头瘤病毒在宫颈癌中作用的理解,为与抗病毒治疗或乳头瘤病毒特异性疫苗相关的预防和治疗策略提供了前景。

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