Vacher-Lavenu M C
Service d'anatomie et de cytologie pathologiques CHU Cochin Port-Royal 27, rue du Faubourg-Saint-Jacques 75679 Paris.
Rev Prat. 2001 Sep 1;51(13):1417-23.
Squamous cell and glandular carcinomas are the two usual forms of cervical cancer. Precancerous and preinvasive lesions must be detected by cervical cancer screening by Pap smears. The Bethesda system is recommended in order to facilitate correlation between cytological and histological diagnosis and to perform the best management of these lesions. Carcinoma in situ and early invasive carcinoma are well known in this situation because of their easy observation. The growing awareness of the role of human papillomavirus with the peculiar cellular modification called koilocytosis, in the carcinogenesis of cervical cancer introduced new possibilities of molecular biology applications.
鳞状细胞癌和腺癌是宫颈癌的两种常见类型。癌前病变和原位癌必须通过巴氏涂片进行宫颈癌筛查来检测。推荐使用贝塞斯达系统,以促进细胞学和组织学诊断之间的关联,并对这些病变进行最佳管理。由于易于观察,原位癌和早期浸润癌在这种情况下是众所周知的。随着人们对人乳头瘤病毒在宫颈癌致癌作用中所起作用的认识不断提高,以及对称为挖空细胞的特殊细胞改变的认识,分子生物学应用出现了新的可能性。