Zhou M, Li X, Geng L, Qu C, Peng S
Department of Clinical Pharmacy, Wuhan Central Railway Hospital, Wuhan 430064.
Zhongguo Zhong Yao Za Zhi. 1998 May;23(5):301-3, inside back cover.
A test was made on the effect of rotundine on the secretion of gastric acid and pepsin activity in rats. Compared with the control group, rotundine(> or = 17.1 mg/kg) inhibited gastric acid and decreased secretion of gastric juice(P < 0.01), but had no influence on pepsin activity. There was a negative relationship between total acidity and pH of gastric juice (r = -0.9818).
进行了罗通定对大鼠胃酸分泌及胃蛋白酶活性影响的试验。与对照组相比，罗通定（≥17.1mg/kg）抑制胃酸分泌，胃液分泌减少（P<0.01），但对胃蛋白酶活性无影响。胃液总酸度与pH呈负相关（r=-0.9818）。
