Schaible R, Hortling N, Stein M, Kreft B
Radiologische Universitätsklinik Bonn.
Laryngorhinootologie. 2001 Oct;80(10):563-8. doi: 10.1055/s-2001-17838.
Aim of this study was to evaluate morphologic criteria for diagnosis of locally recurrent head and neck tumors in helical CT.
Retrospective study, 44 examinations with radiologically abnormal findings were re-read by two radiologists; findings were analysed and correlated with histological diagnosis and clinical findings.
25 cases of local tumor recurrence were confirmed histologically. The accuracy of helical-CT in our preselected examinations for a local tumor recurrence was 93.5 %, the specificity 83.3 %. But 13/44 cases showed radiologically equivocal findings, among them 6 tumor recurrences. The most common characteristics of the 25 proven tumor recurrences were: contrast medium enhancement (96 %), increased volume in comparison to previous examination (92 %), inhomogenity (72 %); however contrast medium-enhancement and increasing volume were also seen in 68.4 % and 63.1 % of the benign changes.
Contrast medium enhancement and increasing volume are criteria with a high sensitivity but low specifity in predicting a local tumor recurrence in head and neck cancer.
本研究的目的是评估螺旋CT诊断头颈部肿瘤局部复发的形态学标准。
回顾性研究,两位放射科医生对44例有放射学异常表现的检查进行重新阅片;对检查结果进行分析,并与组织学诊断及临床检查结果进行对比。
经组织学证实25例为局部肿瘤复发。在我们预先选择的检查中,螺旋CT诊断局部肿瘤复发的准确率为93.5%,特异性为83.3%。但44例中有13例显示放射学表现不明确,其中6例为肿瘤复发。25例经证实的肿瘤复发的最常见特征为:造影剂增强(96%)、与之前检查相比体积增大(92%)、不均匀性(72%);然而,68.4%的良性病变和63.1%的良性病变也可见造影剂增强和体积增大。
造影剂增强和体积增大在预测头颈部癌局部肿瘤复发方面是敏感性高但特异性低的标准。