Puertas A, Paz Carrillo M, Moltó L, Alvarez M, Sedeño S, Miranda J A
Department of Obstetrics and Gynecology, Virgen de las Nieves University Hospital, Avda de las Fuerzas Armadas s/n, 18014 Granada, Spain.
Eur J Obstet Gynecol Reprod Biol. 2001 Nov;99(1):33-7. doi: 10.1016/s0301-2115(01)00354-2.
To investigate the effect of amnioinfusion in women with meconium-stained amniotic fluid on the rate of cesarian sections and on neonatal morbidity.
A randomized controlled trial. A total of 206 women with meconium-stained amniotic fluid were assigned to receive amnioinfusion via two-way catheter or no amnioinfusion (control group). The catheter was inserted and other treatment was the same in both groups.
Amnioinfusion decreased the rate of cesarian sections for fetal distress (RR 0.23, 95% CI 0.07-0.79) and increased mean pH at birth (7.24+/-0.1 versus 7.21+/-0.1, P<0.05). It also decreased the frequency of variable fetal heart rate decelerations (RR 0.74, 95% CI 0.59-0.92), and of meconium below the vocal cords in neonates (RR 0.37, 95% CI 0.19-0.69).
Amnioinfusion improves the neonatal outcome and reduces the frequency of cesarian sections.
探讨羊水灌注对羊水粪染产妇剖宫产率及新生儿发病率的影响。
一项随机对照试验。共有206例羊水粪染产妇被分配接受经双向导管进行羊水灌注或不进行羊水灌注（对照组）。两组均插入导管且其他治疗相同。
羊水灌注降低了因胎儿窘迫而行剖宫产的比率（相对危险度0.23，95%可信区间0.07 - 0.79），并提高了出生时的平均pH值（7.24±0.1对7.21±0.1，P<0.05）。它还降低了胎儿心率变异减速的频率（相对危险度0.74，95%可信区间0.59 - 0.92）以及新生儿声带以下胎粪的出现频率（相对危险度0.37，95%可信区间0.19 - 0.69）。
羊水灌注可改善新生儿结局并降低剖宫产频率。
