Kedar A, Ghoorah J, Thomas P R, Mindell E R, Tebbi C K, Freeman A I
Med Pediatr Oncol. 1979;7(2):163-7. doi: 10.1002/mpo.2950070209.
A 12 1/2-year-old female presented with Ewing's sarcoma of the manubrium sterni which extended into the anterior mediastinum. At presentation there was no evidence of metastatic disease. Her initial treatment consisted of radiation therapy and chemotherapy. The residual tumor was subsequently resected and the sternal defect was repaired with Marlex mesh. Postoperatively, she was maintained on chemotherapy consisting of BCNU, cyclophosphamide, and adriamycin. The adriamycin was discontinued after she developed sterile fibrinous pericarditis. She remains free of her disease two years after diagnosis. Although extremely rare, Ewing's does occur in the sternum and this area is amenable to wide local resection without severe functional disability.
一名12岁半的女性因胸骨柄尤因肉瘤就诊，肿瘤已延伸至前纵隔。就诊时无转移疾病证据。她最初接受了放疗和化疗。随后切除了残留肿瘤，并用Marlex网片修复了胸骨缺损。术后，她继续接受由卡氮芥、环磷酰胺和阿霉素组成的化疗。在她出现无菌性纤维素性心包炎后停用了阿霉素。诊断后两年她仍未复发。尽管极为罕见，但尤因肉瘤确实可发生于胸骨，且该部位适合进行广泛局部切除，不会导致严重功能残疾。
