Ketai R
Postgrad Med. 1975 Oct;58(4):87-93. doi: 10.1080/00325481.1975.11714170.
Antipsychotic drugs are the agents of choice for the management of acute functional psychoses. In most instances, hourly intramuscular injections of chlorpromazine or haloperidol will bring tranquilization within six hours or less. These drugs also are useful in amphetamine-induced psychoses. In psychosis resulting from hallucinogen, however, an antipsychotic drug should be given only as a last resort. In many organic psychoses, including psychosis due to ingestion of an atropine-like drug, use of anti-psychotic drug should be avoided. Before any drug is given to a psychotic patient, an effort should be made to identify an organic brain syndrome, characterized by clouded sensorium, disorientation, and poor recent memory.
抗精神病药物是治疗急性功能性精神病的首选药物。在大多数情况下,每小时肌肉注射氯丙嗪或氟哌啶醇可在6小时或更短时间内使患者镇静下来。这些药物对苯丙胺所致精神病也有效。然而,在致幻剂所致精神病中,抗精神病药物应仅作为最后手段使用。在许多器质性精神病中,包括因摄入类阿托品药物所致的精神病,应避免使用抗精神病药物。在给精神病患者使用任何药物之前,应努力识别一种以意识模糊、定向障碍和近期记忆差为特征的器质性脑综合征。