Barahona A
Departamento de Biología, Universidad Nacional autónoma de México, D.F.
Arch Int Hist Sci (Paris). 1997 Dec;46(137):309-29.
Barbara McClintock was awarded Nobel Prize in Physiology or Medicine in 1983 for the discovery and characterization of jumping genes or transposons. In 1948 she described for the first time maize controlling elements. She proposed 'transposition' as a mechanism that relates phenotypic characteristics with the presence of unstable genes. This discovery was 'ignored' even though she was recognized as a brilliant cytogeneticist. In this paper I approach the matter of the maize research groups within which McClintock developed all of her work, and the problem of variegation in relation to unstable genes and transposition.
芭芭拉·麦克林托克因发现并描述跳跃基因或转座子，于1983年被授予诺贝尔生理学或医学奖。1948年，她首次描述了玉米控制元件。她提出“转座”是一种将表型特征与不稳定基因的存在联系起来的机制。尽管她被公认为杰出的细胞遗传学家，但这一发现却被“忽视”了。在本文中，我探讨了麦克林托克开展其所有研究工作的玉米研究团队相关事宜，以及与不稳定基因和转座有关的斑驳问题。
