Thomson L F, Smith A R, Humphrey R M
Radiology. 1975 Oct;117(1):155-8. doi: 10.1148/117.1.155.
The response of a human malignant melanoma cell line in vitro to high linear energy transfer radiation was studied utilizing the neutrons produced by the reaction of 16 and 50 MeV deuterons on beryllium. The relative biological effectiveness (RBE) relative to cobalt-60 gamma radiation was determined under conditions of complete oxygenation. The data indicate that the radioresistance ascribed to malignant melanoma in vivo is not an intrinsic quality of the cell but rather may be mediated by the in vivo environment.
利用16兆电子伏和50兆电子伏的氘核与铍反应产生的中子，研究了一种人类恶性黑色素瘤细胞系在体外对高传能线密度辐射的反应。在完全充氧的条件下，测定了相对于钴-60γ辐射的相对生物效应（RBE）。数据表明，体内恶性黑色素瘤的放射抗性并非细胞的固有特性，而是可能由体内环境介导。
