Duckett S, Stern J
Jefferson Medical College of the Thomas Jefferson University, Philadelphia, PA, USA.
J Hist Neurosci. 1999 Apr;8(1):21-34. doi: 10.1076/jhin.8.1.21.1771.
A review of the publications of Hans Creutzfeldt and Alfons Jakob pertaining to the concept which bears their name (CJD) reveals that they described a neuropathological syndrome and were opposed to its classification as a neurological disease. The evidence on which Creutzfeldt and Jakob based their view is reevaluated, and studies by other workers are cited in which a range of environmental and genetic factors generated the CJ syndrome, challenging the proposition that CJD is a disease with a single cause.
对汉斯·克雅二氏（Hans Creutzfeldt）和阿尔方斯·雅各布（Alfons Jakob）有关以他们名字命名的概念（克雅二氏病，CJD）的出版物进行回顾后发现，他们描述了一种神经病理学综合征，并且反对将其归类为一种神经系统疾病。重新评估了克雅二氏（Creutzfeldt）和雅各布（Jakob）形成其观点所依据的证据，并引用了其他研究人员的研究，其中一系列环境和遗传因素导致了克雅二氏综合征，这对克雅二氏病是单一病因疾病这一观点提出了挑战。
