Finger S
J Hist Neurosci. 1999 Dec;8(3):269-85. doi: 10.1076/jhin.8.3.269.1824.
Margaret Kennard was an American pioneer in the experimental study of sparing and recovery of function. Her most famous experiments were performed on monkeys and apes at Yale University during the late 1930s and early 1940s. By describing the behavioral effects of brain damage on infantile, juvenile, and older primates, she drew new attention to just how important developmental status can be at the time of neural insult. Kennard also conducted experiments which showed that even adult primates can exhibit significant sparing and recovery of function, especially if brain lesions are made in stages rather than all at once. In many respects, Kennard helped launch the modern era of research on sparing and recovery of function by demonstrating that several factors in addition to lesion locus can affect post-injury performance and by recognizing that, if neural reorganization does occur, it probably takes place in spared parts of the damaged system.
玛格丽特·凯纳德是功能保留与恢复实验研究领域的美国先驱。她最著名的实验是在20世纪30年代末和40年代初于耶鲁大学对猴子和猿类进行的。通过描述脑损伤对幼年、青少年和成年灵长类动物行为的影响，她让人们重新关注到神经损伤发生时发育状态的重要性。凯纳德还进行了实验，结果表明即使是成年灵长类动物也能表现出显著的功能保留与恢复，尤其是如果脑损伤是分阶段而非一次性造成的。在许多方面，凯纳德通过证明除损伤部位外的几个因素会影响损伤后的表现，并认识到如果神经重组确实发生，它可能发生在受损系统的未受损部分，从而推动了功能保留与恢复研究的现代时代。
