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[德国动物病毒学的开端]

[The beginnings of animal virology in Germany].

作者信息

Horzinek M C

出版信息

Argos. 1997(17):267-71.

PMID:11625169
Abstract

Animal virology started in 1898 with the discovery of FMD virus. The finding resulted from a close collaboration between Friedrich Löffler (University of Greifswald) and Paul Frosch (then at Robert Koch's institute in Berlin). Their work in Greifswald was greatly hampered by the danger of dissemination of foot and mouth disease in the surroundings. Therefore Löffler proposed to set up a research unit on the Island of Riems in the Baltic Sea. In the Fall of 1910 work could start in the Research Institute Riems Island. A great foreward step was set when Löffler's successor, prof. Otto Waldmann, succeeded in 1920 in transmitting the infection to guinea pigs by intradermal inoculation in the hind pad. Under Waldmann's aegis the Riems developed into a full-fledged FMD research station. The most important achievement for veterinary medicine was the development of a vaccine in 1938 that proved efficient and safe. Today, the Riems laboratories form part of the Federal Research Centre for Virus Diseases of Animals, together with the Tübingen Unit.

摘要

动物病毒学始于1898年口蹄疫病毒的发现。这一发现是弗里德里希·勒夫勒(格赖夫斯瓦尔德大学)和保罗·弗罗施(当时在柏林的罗伯特·科赫研究所)密切合作的结果。他们在格赖夫斯瓦尔德的工作因口蹄疫在周边地区传播的危险而受到极大阻碍。因此,勒夫勒提议在波罗的海的里姆斯岛上设立一个研究单位。1910年秋,里姆斯岛研究所开始运作。1920年,勒夫勒的继任者奥托·瓦尔德曼教授成功地通过在后脚垫皮内接种将感染传播给豚鼠,这是向前迈出的一大步。在瓦尔德曼的主持下,里姆斯发展成为一个成熟的口蹄疫研究站。兽医学最重要的成就是在1938年研制出一种证明有效且安全的疫苗。如今,里姆斯实验室与图宾根研究单位一起,成为联邦动物病毒病研究中心的一部分。

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