Austin G, Laffin D, Hayward W
Ann Clin Lab Sci. 1975 Jul-Aug;5(4):229-35.
The high incidence of stroke has been considered and the importance of measuring cerebral blood flow (CBF) in patients with transient ischemic attacks has been emphasized. A brief description has been given of the non-invasive method of measuring CBF using a brief bolus injection of 133xenon into any convenient arm vein. The values of CBFg = 75 +/- 8 and CBFw = 24 +/- 2 in ml per 100 g per M compared closely to those obtained by the internal carotid method of measurement. Cerebral blood flow in the gray matter, CBFg is the more sensitive measurement and is used almost exclusively to evaluate patients undergoing microneurosurgical anastomosis for cerebral ischemia in an attempt to prevent or modify stroke. The post operative studies in patients who had a pre operative depression of CBFg greater than 2 S.D. showed improvement in both the frontal and parietal regions. The latter was more significant with p less than 0.04 using paired t-tests.
已考虑到中风的高发病率，并强调了在短暂性脑缺血发作患者中测量脑血流量（CBF）的重要性。已简要描述了一种非侵入性测量CBF的方法，即通过在任何方便的手臂静脉中快速推注133氙。每100克每M的CBFg值为75±8和CBFw值为24±2，与通过颈内动脉测量方法获得的值密切相关。灰质中的脑血流量CBFg是更敏感的测量指标，几乎专门用于评估因脑缺血而接受显微神经外科吻合术以预防或改善中风的患者。术前CBFg降低大于2个标准差的患者术后研究显示，额叶和顶叶区域均有改善。使用配对t检验，后者更显著，p小于0.04。
