Pereles F S, Kapoor V, Carr J C, Simonetti O P, Krupinski E A, Baskaran V, Finn J P
Department of Radiology, Northwestern University Medical School, 676 N. St. Clair, Ste. 800, Chicago, IL 60611, USA.
AJR Am J Roentgenol. 2001 Nov;177(5):1155-60. doi: 10.2214/ajr.177.5.1771155.
The purpose of this study is to compare ultrashort TR, segmented trueFISP (fast imaging with steady-state precession) cine MR imaging with segmented FLASH (fast low-angle shot) cine MR imaging for the detection and characterization of congenital and acquired adult cardiac abnormalities.
Twenty-five patients with known or clinically suspected cardiac abnormalities were imaged on a 1.5-T scanner. Valve plane movies were obtained in patients with suspected valve morphology or function abnormalities or whose horizontal long-axis images showed jets. For each patient, three radiologists independently compared corresponding matched cine FLASH and trueFISP movies for image quality in evaluating anatomy and function of the great vessels and heart. Image quality was rated on a five-point scale, and data were analyzed using both a Wilcoxon's signed rank test and a repeated-measures analysis of variance.
Image quality ratings of trueFISP and FLASH showed a statistically significant difference (F = 58.67; df = 1, 72; p < 0.0001), with the average rating for the trueFISP images being significantly higher (mean rating, 4.1 +/- 0.92) than that for the FLASH images (mean, 3.0 +/- 1.0). However, valve architecture in the aortic valves appeared to be better visualized and was more easily measured in valve plane images with FLASH. No statistically significant differences among the ratings of the interpreters (F = 0.018; df = 2, 72; p = 0.9821) were evident, and, therefore, no suggestion of bias was indicated (F = 0.775; df = 1, 2; p = 0.4645). TrueFISP yielded the correct diagnosis prospectively in 13 (100%) of 13 patients, whereas FLASH yielded the correct diagnosis in 12 (92%) of 13 patients.
TrueFISP images depict morphologic and functional abnormalities with greater clarity and provide greater diagnostic confidence than FLASH images-and in a fraction of the time. A specific exception is in the assessment of valve leaflet architecture and cross-sectional area calculation (i.e., bicuspid aortic valves); in these evaluations, FLASH maintains a complementary diagnostic imaging role.
本研究旨在比较超短TR分段稳态进动快速成像(trueFISP)电影磁共振成像与分段快速低角度激发(FLASH)电影磁共振成像在检测和鉴别先天性及后天性成人心脏异常方面的效果。
25例已知或临床怀疑有心脏异常的患者在1.5-T扫描仪上进行成像。对怀疑有瓣膜形态或功能异常或其水平长轴图像显示有血流喷射的患者获取瓣膜平面电影。对于每位患者,三名放射科医生独立比较相应匹配的FLASH和trueFISP电影在评估大血管和心脏解剖结构及功能时的图像质量。图像质量按五分制评分,并使用Wilcoxon符号秩检验和重复测量方差分析对数据进行分析。
trueFISP和FLASH的图像质量评分显示出统计学显著差异(F = 58.67;自由度 = 1, 72;p < 0.0001),trueFISP图像的平均评分(平均评分,4.1 +/- 0.92)显著高于FLASH图像(平均评分,3.0 +/- 1.0)。然而,在主动脉瓣的瓣膜结构方面,FLASH的瓣膜平面图像似乎能更好地显示且更易于测量。在解释者的评分之间没有明显的统计学显著差异(F = 0.018;自由度 = 2, 72;p = 0.9821),因此,没有显示出偏差的迹象(F = 0.775;自由度 = 1, 2;p = 0.4645)。trueFISP在13例患者中的13例(100%)前瞻性地得出了正确诊断,而FLASH在13例患者中的12例(92%)得出了正确诊断。
trueFISP图像能更清晰地描绘形态和功能异常,比FLASH图像提供更高的诊断信心——而且所需时间更短。一个特定的例外是在评估瓣膜小叶结构和横截面积计算(即二叶式主动脉瓣)时;在这些评估中,FLASH保持着辅助诊断成像的作用。