Grabowska M, Michaluk J, Antkiewicz L
Arch Immunol Ther Exp (Warsz). 1975;23(4):505-9.
The influence of NBTI, an agent which stimulated dopamine receptor in the central nervous system, on concentrations of serotonin and its metabolic, 5-hydroxyindoleacetic acid in the brain of rats was studied. Turnover rate of serotonin in the brain after administration of NBTI to normal rats and those pretreated with spiroperidol, a factor which blocks central dopamine receptors, was evaluated. The changes in metabolism of brain serotonin under the influence of NBTI are similar to those produced by another factor which stimulates central dopamine receptors, namely apomorphine. NBTI causes transient increase in exploratory activity of rats and lowers body temperature.
研究了NBTI（一种刺激中枢神经系统多巴胺受体的物质）对大鼠脑中血清素及其代谢产物5-羟吲哚乙酸浓度的影响。评估了向正常大鼠以及预先用阻断中枢多巴胺受体的因子氟哌啶醇处理过的大鼠施用NBTI后，脑中血清素的周转率。NBTI影响下脑血清素代谢的变化与另一种刺激中枢多巴胺受体的因子阿扑吗啡所产生的变化相似。NBTI导致大鼠探索活动短暂增加并降低体温。
