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对暴露于失重状态的大鼠小脑的代特核和小结皮质进行定量细胞化学和组织化学研究。

Quantitative cyto- and histochemical studies of the Deiter's nucleus and nodular cortex of cerebellum in rats exposed to weightlessness.

作者信息

Krasnov I B

出版信息

Aviat Space Environ Med. 1975 Sep;46(9):1119-22.

PMID:1164346
Abstract

Spaceflight aboard the "Cosmos-605" artificial satellite during 22 d does not have a substantial effect upon the activity of enzymes involved in energy metabolism--lactate dehydrogenase and creatine kinase--in cytoplasm of the giant neurons of the dorsocaudal part of the Deiters' nucleus and cortex layers of the cerebellar nodulus in rats. At the same time, on the second postflight day, in the molecular layer of cerebellar nodulus in rats flown for 22 d in space, some increase in lipid content was noted, probably connected with quantitative or qualitative changes in afferent impulses from the vestibular apparatus to the nodulus. On the 27th postflight day, lipid content in the molecular layer returned to the level observed in rats during ground-based experiments.

摘要

大鼠乘坐“宇宙-605”人造卫星进行22天的太空飞行,对其Deiters核背尾侧部分的大神经元细胞质以及小脑小结皮质层中参与能量代谢的酶——乳酸脱氢酶和肌酸激酶的活性没有实质性影响。同时,在飞行后第二天,太空飞行22天的大鼠小脑小结分子层中,脂质含量有所增加,这可能与从前庭器官到小结的传入冲动的数量或质量变化有关。在飞行后第27天,分子层中的脂质含量恢复到地面实验中大鼠所观察到的水平。

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