Dines D E, Pierre R V, Franzen S J
Mayo Clin Proc. 1975 Oct;50(10):571-2.
Fifty samples of pleural fluid, collected from consecutive patients in a thoracic clinic who had diagnostic thoracentesis, were studied prospectively. Pleural fluid protein was of value in differentiating transudates from exudates. Pleural fluid red cell counts, white blood cell counts, and differential white blood cell counts have no specificity and no usefulness in the differential diagnosis of the origin of the effusion. Pleural fluid cytology was positive in 60% of all the malignancies studied in this series; for the group with metastatic breast carcinoma, there was a 78% positive pleural fluid cytology. Differential white cell counts revealed tumor cells in 45% of malignant effusions. In our experience, the finding of tumor cells is the only useful finding in differential cell counts of the pleural fluid.
前瞻性研究了从一家胸科诊所连续接受诊断性胸腔穿刺术的患者中采集的50份胸水样本。胸水蛋白对区分漏出液和渗出液有价值。胸水红细胞计数、白细胞计数及白细胞分类计数在鉴别胸腔积液的病因方面无特异性且无用处。在本系列研究的所有恶性肿瘤中，胸水细胞学检查阳性率为60%；对于转移性乳腺癌组，胸水细胞学检查阳性率为78%。白细胞分类计数显示，45%的恶性胸腔积液中有肿瘤细胞。根据我们的经验，在胸水细胞分类计数中，发现肿瘤细胞是唯一有用的发现。
