Di Nola F
Minerva Med. 1975 Sep 1;66(56):2763-75.
There are several stages in the management of purulent bacterial meningitis: anti-infective measures, respiratory resuscitation, treatment of mechanical neurological complications, sepsis and shock. The way in which ordinary antibiotics cross the blood-brain barrier is described, together with the anti-infective treatment of choice applicable to different aetiologies. A series of cases is presented. It is felt that, in spite of the positive influence exerted by antibiotics, the treatment of purulent bacterial meningitis is still a complex matter. In addition to careful selection of a drug against infection, rational use must be made of various forms of treatment to prevent respiratory infufficiency, neurological complications, sepsis and shock.
抗感染措施、呼吸复苏、机械性神经并发症的治疗、败血症和休克的治疗。文中描述了普通抗生素穿过血脑屏障的方式，以及适用于不同病因的抗感染治疗选择。还列举了一系列病例。人们认为，尽管抗生素发挥了积极作用，但化脓性细菌性脑膜炎的治疗仍然是一件复杂的事情。除了谨慎选择抗感染药物外，还必须合理运用各种治疗方式以预防呼吸功能不全、神经并发症、败血症和休克。
