Hilliard J, Pang C N, Penardi R, Sawyer C H
Proc Soc Exp Biol Med. 1975 Sep;149(4):1010-4. doi: 10.3181/00379727-149-38945.
Levels of testosterone (T) and LH in the peripheral serum of male and female rabbits were measured and compared following coitus. Blood was collected by heart puncture from restrained, unanesthetized animals of both sexes. In male rabbits, basal serum T levels were highly variable, ranging from 131 to 12,149 pg/ml, and if low preceding coitus they tended to rise; whereas, if high, they usually dropped as they did in nonmated males subjected to repeated heart punctures. In contrast, basal serum LH levels in males were quite constant (mean +/- SE, 1993 +/- 152 pg/ml) and were not significantly altered after coitus unless blood T levels had been drastically lowered by two priming doses of estradiol benzoate. In intact does, on the other hand, copulation which resulted in ovulation induced an approximately 20-fold increase in serum LH concentration which was sustained for about 4 hr. Postcoital elevations in serum LH also occurred in estrogen-primed intact and estrogen-primed ovariectomized does. Under the conditions of our experiments, the parallel elevations in serum LH and T observed postcoitally in the female rabbit could not be demonstrated in the male.
在交配后，对雄性和雌性兔子外周血清中的睾酮（T）和促黄体生成素（LH）水平进行了测量和比较。通过心脏穿刺从未麻醉的、被约束的雌雄动物中采集血液。在雄性兔子中，基础血清T水平变化很大，范围从131到12149 pg/ml，如果交配前水平较低，它们往往会升高；而如果水平较高，它们通常会下降，就像在接受反复心脏穿刺的未交配雄性兔子中一样。相比之下，雄性兔子的基础血清LH水平相当恒定（平均值±标准误，1993±152 pg/ml），除非血液T水平因两次苯甲酸雌二醇预给药而大幅降低，否则交配后不会有显著变化。另一方面，在完整的雌兔中，导致排卵的交配会使血清LH浓度增加约20倍，并持续约4小时。在雌激素预处理的完整雌兔和雌激素预处理的去卵巢雌兔中，交配后血清LH也会升高。在我们的实验条件下，在雄性兔子中无法证明交配后在雌性兔子中观察到的血清LH和T的平行升高。
