Van Dijk J E, Van der Molen E J, De Smidt A C
Tijdschr Diergeneeskd. 1975 Jun 1;100(11):604-15.
A case of avian tuberculosis in a horse, with fatal course, is reported. The animal was imported from Poland and became ill after some weeks, in the beginning showing non-specific symptoms which became more severe until death supervened. Post-mortem examination showed a generalised form of tuberculosis. The most important lesions were seen in the lungs, liver, kidneys, spleen, intestinal tract, bones, bone marrow, and the internal lymph nodes. Beside chronic proliferative tuberculosis of the organs, many exudative foci were found with remarkably abundant acid fast bacilli. Mixed lesions were seen, too. Mycobacterium avium was isolated in microbiological examination. The pathogenesis of the infection, the predisposing factors leading to this generalised and open form of tuberculosis and the increasing importance of avian tuberculosis for animals and man are discussed.
报道了一例马患禽结核病并致死的病例。该动物从波兰进口,几周后发病,起初表现为非特异性症状,症状逐渐加重直至死亡。尸检显示为全身性结核病。最重要的病变见于肺、肝、肾、脾、肠道、骨骼、骨髓和内脏淋巴结。除了器官的慢性增生性结核病外,还发现许多渗出性病灶,其中抗酸杆菌大量存在。也可见混合性病变。微生物学检查分离出鸟分枝杆菌。讨论了感染的发病机制、导致这种全身性开放性结核病的易感因素以及禽结核病对动物和人类日益增加的重要性。