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鸡胚造血细胞的不同放射敏感性。

Different radiosensitivity of hematopoietic cells in chick-embryos.

作者信息

Knezević Z A, Petrović N V, Radivojević D V, Millić O B

出版信息

Strahlentherapie. 1975 Jul;150(1):70-5.

PMID:1166477
Abstract

Embryos of different ages from 24th to 120th hour of incubation were irradiated with a dose of 700 R gamma rays at a rate of 50 R/min. After irradiation peripheral blood was taken every 24 hours in order to control proliferation dynamics of megaloblastic and normoblastic cells. The results have shown that the cells of megaloblastic strain reduce much more the mitotic activity that those of normoblastic line. Although the cells of both strains after irradiation show depression in the proliferative activity, in transfer to polychromatophilic forms, megaloblasts disappear almost completely until normoblasts recover spontaneously. The nature of different radiosensitivity in these cell strains has been discussed.

摘要

将孵化24小时至120小时不同年龄的胚胎以50伦琴/分钟的剂量率照射700伦琴的γ射线。照射后每24小时采集外周血,以控制巨幼红细胞和正常幼红细胞的增殖动态。结果表明,巨幼红细胞系的细胞有丝分裂活性比正常幼红细胞系的细胞降低得更多。虽然两种细胞系的细胞在照射后增殖活性均降低,但在向多染性形态转化时,巨幼红细胞几乎完全消失,直到正常幼红细胞自发恢复。讨论了这些细胞系中不同放射敏感性的性质。

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