Olkowski Z L, McLaren J R
Strahlentherapie. 1975 Jul;150(1):76-9.
Quantitative analysis of RNA content was carried out in the oligodendroglia apposed to motor neurons and oligodendrocytes located far from the perikaryons in the spinal cord of mice subjected to 630 rd of whole body gamma irradiation. Decrease of relative RNA content in the glial cells apposed to the neuronal body in the irradiated animals 30 min to one hour after irradiation and the increase of RNA content in these cells two to eight hours after radiation was found. Glia located far from the perikaryons of motor neurons reacted with increase of RNA content 30 min after irradiation and its sharp decrease one hour later. This difference in the reaction of glia to whole body irradiation may be due to different metabolic patterns between glia linked to neurons in neuroglial unit and glia located far from perikaryons.
对接受630拉德全身γ射线照射的小鼠脊髓中与运动神经元相邻的少突胶质细胞以及远离神经元胞体的少突胶质细胞进行了RNA含量的定量分析。发现在照射后30分钟至1小时，受照射动物中与神经元胞体相邻的神经胶质细胞的相对RNA含量降低，而在照射后2至8小时这些细胞中的RNA含量增加。远离运动神经元胞体的神经胶质细胞在照射后30分钟RNA含量增加，1小时后急剧下降。神经胶质细胞对全身照射反应的这种差异可能是由于神经胶质单元中与神经元相连的神经胶质细胞和远离神经元胞体的神经胶质细胞之间不同的代谢模式所致。
