Everett H C
Am J Psychiatry. 1975 Nov;132(11):1202-4. doi: 10.1176/ajp.132.11.1202.
The author describes the use of bethanechol chloride to relieve side effects, including salivary inactivation, constipation, and bladder inhibition, which result from the anticholinergic action of tricyclic antidepressants. He suggests that the use of cholinergic medication during antidepressant therapy may extend the use of the tricyclics to patients who find anticholinergic side effects especially troublesome.
作者描述了使用氯化贝胆碱来缓解副作用，这些副作用包括唾液失活、便秘和膀胱抑制，它们是由三环类抗抑郁药的抗胆碱能作用引起的。他建议在抗抑郁治疗期间使用胆碱能药物，这可能会将三环类药物的适用范围扩大到那些发现抗胆碱能副作用特别麻烦的患者。
