1987 - 1997年美国农场工人联合会（UFW）的癌症发病率。

Cancer incidence in the United Farmworkers of America (UFW), 1987-1997.

作者信息

Mills P K, Kwong S

机构信息

Cancer Registry of Central California, 1320 E. Shaw Ave. Suite 160, Fresno, California 93710, USA.

出版信息

Am J Ind Med. 2001 Nov;40(5):596-603. doi: 10.1002/ajim.1125.

DOI:10.1002/ajim.1125

PMID:11675630

Abstract

BACKGROUND

The purpose of this study was to evaluate cancer incidence in the membership a largely Hispanic farmworker labor union in California, the United Farmworkers of America (UFW) and to examine cancer-site specific distributions as well as histology and stage of cancer at diagnosis in this group.

METHODS

An electronic record linkage was conducted between a membership roster of the UFW and the database of the California Cancer Registry, the population-based cancer registry in California for the years 1987-1997. Based upon the results of the linkage, morbidity odds ratios were calculated using the distribution of cancer in the California Hispanic population as the reference to determine if risk of specific cancers was higher or lower in the UFW. Time since first joining the union was evaluated, as was the proportional distribution of histologic subtypes and stage at diagnosis, again comparing the experience of the UFW membership to the California Hispanic population.

RESULTS

Several types of cancer were elevated in the UFW membership in comparison to the California Hispanic population. Morbidity odds ratios and 95% confidence limits were elevated for leukemia (O.R. = 1.59: 95% C.I. = 1.07-2.37), stomach cancer (O.R. = 1.69: 95% C.I. = 1.24-2.27), uterine cervix cancer (O.R. = 1.63: 95% C.I. = 1.11-2.44) and uterine corpus cancer (O.R. = 1.68: 95% C.I. = 1.05-2.67). Brain cancer was also elevated although not significantly so (O.R. = 1.57: 95% C.I. = 0.96-2.53).

CONCLUSIONS

Risk of leukemia, stomach, cervix and uterine cancers was elevated in California farmworkers. The histologic distribution of leukemia and brain cancers within the UFW membership did not differ from the distribution in the general California population although small numbers of cancers in the UFW hindered interpretation of these results. Members of the UFW experienced later stage of disease at diagnosis in comparison to California Hispanics for most major cancer sites but not for breast cancer.

摘要

背景

本研究旨在评估加利福尼亚州一个主要由西班牙裔农场工人组成的工会——美国农业工人联合会（UFW）会员中的癌症发病率，并研究该群体中癌症部位的具体分布以及诊断时癌症的组织学类型和分期。

方法

在UFW的会员名册与加利福尼亚癌症登记处（1987 - 1997年加利福尼亚州基于人群的癌症登记处）的数据库之间进行了电子记录链接。根据链接结果，以加利福尼亚西班牙裔人群中的癌症分布为参考计算发病比值比，以确定UFW中特定癌症的风险是更高还是更低。评估了自首次加入工会以来的时间，以及诊断时组织学亚型和分期的比例分布，并再次将UFW会员的情况与加利福尼亚西班牙裔人群进行比较。

结果

与加利福尼亚西班牙裔人群相比，UFW会员中几种类型的癌症发病率有所升高。白血病（比值比 = 1.59：95%置信区间 = 1.07 - 2.37）、胃癌（比值比 = 1.69：95%置信区间 = 1.24 - 2.27）、子宫颈癌（比值比 = 1.63：95%置信区间 = 1.11 - 2.44）和子宫体癌（比值比 = 1.68：95%置信区间 = 1.05 - 2.67）的发病比值比和95%置信区间均有所升高。脑癌发病率也有所升高，尽管不显著（比值比 = 1.57：95%置信区间 = 0.96 - 2.53）。