Janssen F
Monatsschr Kinderheilkd (1902). 1975 Jan;123(1):34-7.
A drug may reach the newborn indirectly from the mother via the umbilical cord or brest milk and by direct application. If the Apgar score after 5 or 10 min decreases in relation to the score of the 1st minute, a depression by drugs has to be considered if other causes are eliminated. Some drugs and typical symptoms are described as for instance diazepam, addiction causing drugs, reserpin and imidazol derivatives. With regard to the direct effect of drugs the danger of the simultaneous application of several remedia is especially pointed out.
药物可通过脐带或母乳从母亲间接传递给新生儿,也可直接用药。如果5分钟或10分钟后的阿普加评分相对于第1分钟的评分下降,在排除其他原因后,必须考虑药物引起的抑制作用。一些药物及其典型症状被描述,例如地西泮、成瘾性药物、利血平和咪唑衍生物。关于药物的直接作用,特别指出了同时使用几种药物的危险性。