Pellicano M, Zullo F, Fiorentino A, Tommaselli G A, Palomba S, Nappi C
Department of Obstetrics, Gynecology and Reproductive Medicine, University of Naples Federico II, Naples, Italy.
Hum Reprod. 2001 Nov;16(11):2295-7. doi: 10.1093/humrep/16.11.2295.
Gamete intra-Fallopian transfer (GIFT) is a successful technique for infertile women, and is performed almost exclusively by laparoscopy under general anaesthesia.
We performed a prospective randomized study of 67 infertile patients to assess the efficacy of minilaparoscopic GIFT under conscious sedation/local anaesthesia (group A) compared with general anaesthesia (group B). Operative and discharge times and pregnancy outcome were evaluated in both groups.
Operative time was similar in both groups. The rate of patients discharged 2 h after surgery was significantly higher in group A. The necessity for postoperative analgesics was significantly higher in group B. No significant differences were noted between the two study groups in terms of pregnancy outcome.
Conscious sedation and local anaesthesia will allow us to perform an outpatient minilaparoscopic GIFT without the need for general anaesthesia. The simplicity of the method, and the quicker discharge time in comparison with general anaesthesia, offer a detectable benefit for patients.
配子输卵管内移植（GIFT）是治疗不孕女性的一项成功技术，几乎仅在全身麻醉下通过腹腔镜进行。
我们对67例不孕患者进行了一项前瞻性随机研究，以评估在清醒镇静/局部麻醉下进行微型腹腔镜GIFT（A组）与全身麻醉（B组）的疗效。对两组的手术时间、出院时间和妊娠结局进行了评估。
两组的手术时间相似。A组术后2小时出院的患者比例明显更高。B组术后使用镇痛药的必要性明显更高。两个研究组在妊娠结局方面未观察到显著差异。
清醒镇静和局部麻醉使我们能够在无需全身麻醉的情况下进行门诊微型腹腔镜GIFT。该方法的简便性以及与全身麻醉相比更快的出院时间，为患者带来了明显的益处。
