Rogers J, Chavin K D, Kratz J M, Mohamed H K, Lin A, Baillie G M, Shafizadeh S F, Baliga P K
Division of Transplant Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Liver Transpl. 2001 Oct;7(10):913-7. doi: 10.1053/jlts.2001.26926.
Hepatic artery thrombosis (HAT) is the most common vascular complication after orthotopic liver transplantation (OLT) and has traditionally been managed with re-OLT. However, several reports have shown that urgent revascularization is frequently an effective means of graft salvage. This most often involves hepatic artery (HA) thrombectomy and thrombolysis, with reestablishment of arterial inflow through a donor iliac artery conduit based on the supraceliac or infrarenal aorta. We report a 46-year-old man who developed HAT 13 days after OLT after angiographic splenic artery embolization to reduce splenic artery steal. A suitable donor iliac artery was not available for arterial reconstruction and could not be obtained from neighboring transplant centers. The patient underwent urgent HA thrombectomy, intrahepatic arterial thrombolysis, and revascularization using an autologous radial artery (RA) conduit based on the supraceliac aorta. The patient is alive more than 1 year after revascularization, with normal liver function and documented flow in the arterial conduit by Doppler ultrasound and arteriography. He has not developed late biliary complications or adverse sequelae of RA harvest. Autologous RA can be safely and successfully used as an aortic-based arterial conduit in urgent revascularization of HAT after OLT. RA should be considered for use in HA revascularization if an adequate donor iliac artery is not available and other potential conduits are not usable or desirable. The availability of autologous RA expands the armamentarium of vascular conduits that can be used in HA revascularization and may help minimize re-OLT for otherwise potentially salvageable liver allografts.
肝动脉血栓形成(HAT)是原位肝移植(OLT)后最常见的血管并发症,传统上采用再次OLT进行治疗。然而,一些报告表明,紧急血管重建术常常是挽救移植肝的有效方法。这通常包括肝动脉(HA)血栓切除术和溶栓治疗,并通过基于腹腔干上方或肾下腹主动脉的供体髂动脉导管重建动脉血流。我们报告了一名46岁男性,在OLT术后13天因血管造影脾动脉栓塞以减少脾动脉盗血而发生HAT。没有合适的供体髂动脉用于动脉重建,且无法从邻近的移植中心获取。患者接受了紧急HA血栓切除术、肝内动脉溶栓,并使用基于腹腔干上方主动脉的自体桡动脉(RA)导管进行血管重建。血管重建术后1年多,患者存活,肝功能正常,多普勒超声和动脉造影显示动脉导管内有血流记录。他没有出现晚期胆道并发症或桡动脉取材的不良后遗症。自体RA可安全、成功地用作OLT术后HAT紧急血管重建中基于主动脉的动脉导管。如果没有足够的供体髂动脉,且其他潜在导管不可用或不理想,则应考虑使用RA进行HA血管重建。自体RA的可用性扩大了可用于HA血管重建的血管导管储备,可能有助于减少对原本可能可挽救的肝移植进行再次OLT的情况。