Alekseev A N, Dubinina E V, Vashukova M A, Volkova L I
Med Parazitol (Mosk). 2001 Jul-Sep(3):3-11.
An attempt was made to compare the Borrelia-TBE-virus interface in Ixodes ticks and in patients. The authors suppose that Borrelia might suppress viral replication in ticks and in TBE-susceptible individuals. Whether antibiotics (particularly representatives of the tetracycline group) may be essential in treating tick-borne diseases is also discussed. Examples of antibiotic suppression of Borrelia that made the clinic presentation of encephalitis more severe as a consequence are analyzed and discussed. The calculated risk for borreliosis or tick-borne encephalitis and the actual morbidity rates were compared. Possible reasons for disagreement in the results are also discussed.
研究人员尝试比较硬蜱和患者体内的疏螺旋体与蜱传脑炎病毒的相互作用。作者推测，疏螺旋体可能会抑制蜱及蜱传脑炎易感个体体内的病毒复制。文中还讨论了抗生素（尤其是四环素类药物）在治疗蜱传疾病中是否必不可少。同时，对因抗生素抑制疏螺旋体而导致脑炎临床症状加重的案例进行了分析和讨论。比较了疏螺旋体病或蜱传脑炎的计算风险与实际发病率，并探讨了结果不一致的可能原因。
