Ciacci C, Cavallaro R, Romano R, Galletta D S, Labanca F, Marino M, Donisi M, Mazzacca G
Department of Internal Medicine, Federico II University of Naples, Italy.
Dig Dis Sci. 2001 Oct;46(10):2206-8. doi: 10.1023/a:1011919100259.
The diagnosis of celiac disease patients may be delayed by misdiagnosis. Our aim was to evaluate in celiac patients the prevalence of surgery before diagnosis. Two hundred forty-four adult celiac patients and 232 controls were retrospectively investigated for surgery before diagnosis of celiac disease. The prevalence of surgery was increased in celiac patients versus controls (P = 0.001). Frequency of appendectomy (P = 0.0001), tonsillectomy (P = 0.009), and hernia repair (P = 0.05) were increased in celiac patients versus controls. Appendectomy was related to anemia (P = 0.006) and abdominal pain (P = 0.005); tonsillectomy was related to diarrhea (P = 0.02) and weight loss (P = 0,04). Appendectomy was elective in 73% of celiac patients and in 46% of controls. Cosmetic surgery was increased in celiac patients versus controls (P = 0.058). In conclusions, surgery before celiac disease diagnosis is increased in celiac patients compared to controls, as a result of doctors' misdiagnosis and/or poor health status, which increases the demand for medical intervention. The frequency of cosmetic surgery in celiac patients may berelated to impaired psychological profile of patients.
乳糜泻患者的诊断可能会因误诊而延迟。我们的目的是评估乳糜泻患者在诊断前接受手术的患病率。对244例成年乳糜泻患者和232例对照者进行回顾性研究，以调查乳糜泻诊断前的手术情况。与对照组相比，乳糜泻患者的手术患病率有所增加（P = 0.001）。与对照组相比，乳糜泻患者的阑尾切除术（P = 0.0001）、扁桃体切除术（P = 0.009）和疝气修补术（P = 0.05）的发生率增加。阑尾切除术与贫血（P = 0.006）和腹痛（P = 0.005）有关；扁桃体切除术与腹泻（P = 0.02）和体重减轻（P = 0.04）有关。73%的乳糜泻患者和46%的对照者的阑尾切除术是选择性的。与对照组相比，乳糜泻患者的美容手术有所增加（P = 0.058）。总之，与对照组相比，乳糜泻患者在疾病诊断前接受手术的情况有所增加，这是由于医生的误诊和/或健康状况不佳，从而增加了医疗干预的需求。乳糜泻患者的美容手术频率可能与患者心理状况受损有关。
