Warren D W, Haltmeyer G C, Eik-Nes K B
Endocrinology. 1975 May;96(5):1226-9. doi: 10.1210/endo-96-5-1226.
Testosterone formation was measured in fetal and neonatal (2 h to 20 days) rat testes incubated with and without 100 IU human chorionic gonadotrophin (hCG). At all ages studied, testosterone production was significantly elevated in the presence of hCG. Neonatal testes showed an absolute drop in testosterone production with increasing age, but the percentage increase above baseline produced by hCG stimulation leads to the speculation that this decrease is due to a relative reduction in the number of Leydig cells with increasing age rather than to a lowered sensitivity to hCG stimulation.
在有和没有100国际单位人绒毛膜促性腺激素（hCG）的情况下，对胎鼠和新生（2小时至20天）大鼠睾丸中睾酮的生成进行了测定。在所有研究的年龄段，hCG存在时睾酮生成显著升高。新生睾丸的睾酮生成随年龄增长出现绝对下降，但hCG刺激引起的相对于基线的百分比增加使人推测，这种下降是由于随着年龄增长，睾丸间质细胞数量相对减少，而非对hCG刺激的敏感性降低所致。
