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一项具有全国代表性的青少年和青年样本中重度抑郁发作的12个月患病率及特征

The 12-month prevalence and characteristics of major depressive episode in a representative nationwide sample of adolescents and young adults.

作者信息

Haarasilta L, Marttunen M, Kaprio J, Aro H

机构信息

National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland.

出版信息

Psychol Med. 2001 Oct;31(7):1169-79. doi: 10.1017/s0033291701004573.

Abstract

BACKGROUND

This study set out to estimate the 12-month prevalence of DSM-III-R major depressive episode (MDE) and to analyse factors associating with psychosocial impairment, episode duration, phenomenology and symptom severity in a representative general population sample of adolescents (15-19-year-olds) and young adults (20-24-year-olds).

METHOD

The Finnish Health Care Survey '96 (FINHCS '96) was a cross-sectional nationwide epidemiological study. A random sample of 509 adolescents and 433 young adults was interviewed in 1996. MDE was assessed by University of Michigan Composite Diagnostic Interview Short-Form.

RESULTS

The 12-month prevalence of MDE was 5.3 % for adolescents (females 6.0%, males 4.4%) and 9.4% for young adults (females 10.7%, males 8.1%). When moderate psychosocial impairment was included in case definition, the prevalences were lowered by 20-25%. Increased impairment was associated with drunkenness at least twice a month, a higher mean number of depressive symptoms and impaired concentration. The median episode duration was 1 month. No factors associating with duration were found. With the exception of symptoms related to appetite being more common among females than males, the phenomenology of MDE was mainly independent of age and gender.

CONCLUSIONS

Episodes of major depression among adolescents and young adults in the general population are short but often associated with psychosocial impairment, especially if frequent drunkenness coexists.

摘要

背景

本研究旨在估计《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)中重度抑郁发作(MDE)的12个月患病率,并分析在具有代表性的青少年(15 - 19岁)和青年成人(20 - 24岁)普通人群样本中,与社会心理损害、发作持续时间、现象学及症状严重程度相关的因素。

方法

芬兰1996年医疗保健调查(FINHCS '96)是一项全国性横断面流行病学研究。1996年,对509名青少年和433名青年成人进行了随机抽样访谈。采用密歇根大学复合诊断访谈简表评估MDE。

结果

青少年中MDE的12个月患病率为5.3%(女性6.0%,男性4.4%),青年成人中为9.4%(女性10.7%,男性8.1%)。若将中度社会心理损害纳入病例定义,患病率降低20 - 25%。损害增加与每月至少两次醉酒、抑郁症状平均数量较多以及注意力不集中有关。发作持续时间的中位数为1个月。未发现与持续时间相关的因素。除食欲相关症状在女性中比男性更常见外,MDE的现象学主要与年龄和性别无关。

结论

普通人群中青少年和青年成人的重度抑郁发作持续时间较短,但常与社会心理损害相关,尤其是在同时存在频繁醉酒的情况下。

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