单侧角膜格子状营养不良。
Unilateral corneal lattice dystrophy.
作者信息
Sridhar M S, Laibson P R, Eagle R C, Rapuano C J, Cohen E J
机构信息
Cornea Service, Wills Eye Hospital, Philadelphia, Pennsylvania 19107, USA.
出版信息
Cornea. 2001 Nov;20(8):850-2. doi: 10.1097/00003226-200111000-00014.
PURPOSE
To report three cases of seemingly unilateral dystrophy indistinguishable from type I classic lattice corneal dystrophy.
METHODS
Case study of three patients. Three patients, a 31-year-old man, a 44-year-old woman, and a 41-year-old man had multiple lattice lesions in one eye and an apparently healthy fellow eye. Two of these patients underwent penetrating keratoplasty because of poor vision.
RESULTS
Histopathologic examination of the excised corneal button of patient 2 showed amyloid deposits consistent with lattice. In the third patient, lattice lesions were noted in the other eye nearly 13 years after he was first examined.
CONCLUSIONS
Lattice corneal dystrophy is rarely unilateral. Lattice, even in unilateral cases, may cause significant vision loss to warrant penetrating keratoplasty. Lattice lesions may develop in the fellow eye many years later. This possibility should be explained to all patients with apparently unilateral lattice corneal dystrophy.
目的
报告三例看似单侧营养不良但与I型经典格子状角膜营养不良难以区分的病例。
方法
对三名患者进行病例研究。三名患者，一名31岁男性、一名44岁女性和一名41岁男性，一只眼睛有多处格子状病变，而另一只眼睛明显健康。其中两名患者因视力差接受了穿透性角膜移植术。
结果
患者2切除的角膜植片的组织病理学检查显示有与格子状相符的淀粉样沉积物。在第三名患者中，首次检查近13年后，另一只眼睛出现了格子状病变。
结论
格子状角膜营养不良很少为单侧。即使是单侧病例，格子状病变也可能导致严重视力丧失，需要进行穿透性角膜移植术。多年后，对侧眼可能会出现格子状病变。对于所有看似单侧格子状角膜营养不良的患者，都应解释这种可能性。
Zotero 插件