Tilganga Institute of Ophthalmology, Gaushala, Nepal.
JNMA J Nepal Med Assoc. 2021 Apr 30;59(236):406-408. doi: 10.31729/jnma.5726.
Granular - lattice (Avellino) corneal dystrophy is inherited in an autosomal dominant fashion which affects stroma of the cornea with recurrent erosions and decreased vision due to clouding of cornea in later stage. We reported a case of 53-year old woman presented with pain and blurring of vision of left eye for 10 days with history of right eye deep anterior lamellar dystrophy and Left eye penetrating keratoplasty 5years back for Avellino dystrophy. On examination right eye graft was clear and left eye showed circular edges of irregular epithelium with patchy stains and epithelial defect suggestive of recurrence of dystrophy. A patient with recurrent corneal erosions and opacity in cornea has to be examined carefully so as not to overlook Avellino corneal dystrophy. Being a rare disorder this case has been reported to draw the attention of ophthalmologists about its recurrence following keratoplasty.
颗粒 - 格子（阿韦利诺）角膜营养不良呈常染色体显性遗传，影响角膜基质，常伴有反复发作的角膜糜烂和视力下降，晚期则因角膜混浊而导致视力下降。我们报告了一例 53 岁女性，左眼疼痛和视力模糊 10 天，右眼曾患有深层前部板层营养不良，5 年前因阿韦利诺营养不良行左眼穿透性角膜移植术。检查发现右眼植片透明，左眼表现为边缘不规则的上皮呈环形，有斑片状染色和上皮缺损，提示营养不良复发。对于反复发作性角膜糜烂和角膜混浊的患者，应仔细检查，以免漏诊阿韦利诺角膜营养不良。由于这种疾病比较罕见，因此报告此病例旨在引起眼科医生对其在角膜移植术后复发的关注。
