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结核病过敏反应中嗜中性粒细胞的损伤机制。

The mechanism of damage to neutrophils in allergic reactions in tuberculosis.

作者信息

Kitaev M I, Zasukhina I B

出版信息

J Hyg Epidemiol Microbiol Immunol. 1975;19(1):85-92.

PMID:1168672
Abstract

Allergic vulnerability of neutrophils due to pulmonary antigen and tuberculin in tuberculosis is connected with the fact that the immunological conflict antigen-antibody takes place on the surface of leukocytes. These two effects have a similar mechanism. The tissue antigen or tuberculin adsorbed on the cell surface with the participation of the complement may react with the corresponding circulating antibodies, thus producing damage to neutrophils.

摘要

结核病中肺部抗原和结核菌素导致的中性粒细胞过敏易感性与免疫冲突抗原-抗体在白细胞表面发生这一事实相关。这两种效应具有相似的机制。在补体参与下吸附在细胞表面的组织抗原或结核菌素可能与相应的循环抗体发生反应,从而对中性粒细胞造成损伤。

相似文献

1
The mechanism of damage to neutrophils in allergic reactions in tuberculosis.结核病过敏反应中嗜中性粒细胞的损伤机制。
J Hyg Epidemiol Microbiol Immunol. 1975;19(1):85-92.
2
The mechanism of agglomeration of leukocytes in allergic reactions in tuberculosis.结核病过敏反应中白细胞聚集的机制。
J Hyg Epidemiol Microbiol Immunol. 1980;24(1):71-6.
3
Cellular and humoral hypersensitivity reactions during silicosis and silicotuberculosis.矽肺和矽肺结核时的细胞和体液超敏反应。
J Hyg Epidemiol Microbiol Immunol. 1978;22(3):278-83.
4
[Allergic changes in the blood neutrophils in pulmonary tuberculosis].[肺结核患者血液中性粒细胞的变态反应性变化]
Sov Med. 1972 Apr;35(4):93-7.
5
[Use of blood serum of patients with pulmonary tuberculosis for potentiation of the reaction of neutrophils to tuberculin].[利用肺结核患者血清增强中性粒细胞对结核菌素的反应]
Probl Tuberk. 1975(1):42-3.
6
[Significance of the immunological indices of specific reactivity in the differential diagnosis of pulmonary tuberculosis and pneumonias].[特异性反应免疫指标在肺结核与肺炎鉴别诊断中的意义]
Vrach Delo. 1980 Apr(4):20-2.
7
[Autoleukocytolysis in pulmonary tuberculosis].[肺结核中的自身白细胞溶解]
Probl Tuberk. 1970;48(12):52-6.
8
Inhibition of leukocyte migration: an evaluation of this in vitro assay of delayed hypersensitivity in man to a soluble antigen.白细胞迁移抑制:对人针对可溶性抗原的迟发型超敏反应的这种体外测定法的评估。
J Immunol. 1970 Dec;105(6):1147-52.
9
[Significance of delayed-type hypersensitivity in the immunity against tuberculous infection].
Probl Tuberk. 1973;51(1):57-63.
10
The method of preparation of an antigen may influence the cellular reaction to it in skin tests for delayed hypersensitivity: comparison between responses to two different reagents prepared from Mycobacterium tuberculosis.在迟发型超敏反应的皮肤试验中,抗原的制备方法可能会影响机体对其产生的细胞反应:对两种由结核分枝杆菌制备的不同试剂的反应比较。
Clin Exp Immunol. 1987 Sep;69(3):584-90.