Adler S M, Denton R L
J Pediatr. 1975 Jun;86(6):942-8. doi: 10.1016/s0022-3476(75)80233-2.
Determination of the erythrocyte sedimentation rate in capillary blood can be of value in identifying neonates with infection. The normal values for the method described here range from 1 mm/l hour at 12 hours of age to 17 mm/l hour at 14 days of age. Most noninfected neonates with moderate to severe RDS or with other serious illness had values well within the normal range. Infected patients had marked elevations, and the majority of values returned to normal with clinical improvement. Coombs-positive ABO hemolytic disease was also responsible for elevated values. In about half of the infected patients the rise was not seen until 24 to 48 hours after clinical symptoms first appeared. The ESR can be useful in the nursery as a preliminary step in the laboratory evaluation of the sick neonate. Serial determinations may be of aid in identifying the infected infant when the results of bacteriologic cultures are obscured by antibiotic therapy.
测定毛细血管血中的红细胞沉降率对于识别感染的新生儿可能有价值。此处所述方法的正常范围为:12小时龄时为1mm/小时,14日龄时为17mm/小时。大多数患有中度至重度呼吸窘迫综合征或其他严重疾病的未感染新生儿的值均在正常范围内。感染患者的值明显升高,且随着临床症状改善,大多数值恢复正常。库姆斯阳性ABO溶血病也可导致值升高。约一半的感染患者直到临床症状首次出现后24至48小时才出现值升高。红细胞沉降率在新生儿病房对患病新生儿进行实验室评估时可作为初步步骤。当细菌培养结果因抗生素治疗而模糊不清时,连续测定可能有助于识别感染婴儿。