Jenkins R A, Maskarinec M P, Counts R W, Caton J E, Tomkins B A, Ilgner R H
Chemical and Analytical Sciences Division, Oak Ridge National Laboratory, PO Box 2008, Oak Ridge, Tennessee 37831-6120, USA.
J Expo Anal Environ Epidemiol. 2001 Sep-Oct;11(5):369-80. doi: 10.1038/sj.jea.7500178.
The objective of this investigation was to determine the extent of areal and day-to-day variability of stationary environmental tobacco smoke (ETS) concentrations in a single large facility where smoking was both prevalent and unrestricted, and to determine the degree of daily variation in the personal exposure levels of ETS constituents in the same facility. The subject facility was a relatively new four-story office building with an approximate volume of 1.3 million ft3. The exchange of outside air in the building was determined to be between 0.6 and 0.7 air changes per hour. Eighty-seven area samples (excluding background) were collected at 29 locations over the course of 6 days of sampling. Locations included offices and cubicles occupied by smokers and nonsmokers, common areas, and the computer and mail rooms. Twenty-four nonsmoking subjects wore personal sampling systems to collect breathing zone air samples on each of 3 days in succession. This generated a total of seventy-two 8-h time-weighted average (TWA) personal exposure samples. In all samples, respirable suspended particulate matter, ultraviolet light-absorbing and fluorescing particulate matter, solanesol, nicotine, and 3-ethenyl pyridine were determined. With the exception of a few locations, tobacco-specific airborne constituents were determined in all samples. Not surprisingly, areas with the highest ETS constituent concentrations were offices and cubicles of smokers. Median and 95th percentile concentrations for all area samples, excluding background, were determined to be 1.5 and 8.7 microg/m3 for nicotine, and 8.2 and 59 microg/m3 for ETS-specific particles (as solanesol-related particulate matter, Sol-PM), respectively. Personal exposure concentrations of ETS components were similar to those levels found in the area samples (median nicotine and Sol-PM concentrations were 1.24 and 7.1 microg/m3, respectively), but the range of concentrations was somewhat smaller. For example, the 95th percentile 8-h TWA nicotine and ETS-specific particle (as Sol-PM) concentrations were 3.58 and 21.9 microg/m3, respectively. Intrasubject variation of daily concentrations ranged from 20% to 60%, depending on the component. Self-reported proximity to smokers was supported by higher ETS concentrations determined from the personal monitors, but only to a modest extent. Although smoking was completely unrestricted inside the main office areas of the facility, ETS levels, either areal or from personal exposure measurements, were lower than those estimated by Occupational Safety and Health Administration to be present in such facilities.
本调查的目的是确定在一个吸烟普遍且不受限制的大型单一设施中,静态环境烟草烟雾(ETS)浓度的区域和每日变化程度,并确定同一设施中ETS成分个人暴露水平的每日变化程度。调查对象设施是一座相对较新的四层办公楼,容积约为130万立方英尺。该建筑的室外空气交换率确定为每小时0.6至0.7次换气。在6天的采样过程中,在29个地点采集了87个区域样本(不包括背景样本)。采样地点包括吸烟者和非吸烟者占用的办公室和小隔间、公共区域以及计算机房和邮件室。24名不吸烟的受试者连续3天佩戴个人采样系统,以采集呼吸带空气样本。这总共产生了72个8小时时间加权平均(TWA)个人暴露样本。在所有样本中,测定了可吸入悬浮颗粒物、紫外线吸收和荧光颗粒物、茄尼醇、尼古丁和3-乙烯基吡啶。除了少数地点外,所有样本中都测定了烟草特异性空气成分。不出所料,ETS成分浓度最高的区域是吸烟者的办公室和小隔间。不包括背景样本的所有区域样本中,尼古丁的中位数和第95百分位数浓度分别确定为1.5和8.7微克/立方米,ETS特异性颗粒物(以与茄尼醇相关的颗粒物,即Sol-PM计)的浓度分别为8.2和59微克/立方米。ETS成分的个人暴露浓度与区域样本中的浓度相似(尼古丁和Sol-PM的中位数浓度分别为1.24和7.1微克/立方米),但浓度范围略小。例如,第95百分位数的8小时TWA尼古丁和ETS特异性颗粒物(以Sol-PM计)浓度分别为3.58和21.9微克/立方米。根据成分不同,个体每日浓度的变化范围在20%至60%之间。个人监测器测定的较高ETS浓度支持了自我报告的与吸烟者的接近程度,但程度有限。尽管该设施主要办公区域内吸烟完全不受限制,但无论是区域浓度还是个人暴露测量浓度,ETS水平都低于美国职业安全与健康管理局估计的此类设施中的水平。