Thyroid autoimmunity.
作者信息
Rapoport B, McLachlan S M
机构信息
Autoimmune Disease Unit, Cedars-Sinai Research Institute and School of Medicine, University of California, Los Angeles, California, USA.
出版信息
J Clin Invest. 2001 Nov;108(9):1253-9. doi: 10.1172/JCI14321.
Abstract
摘要
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本文引用的文献
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Search for the autoantibody immunodominant region on thyroid peroxidase: epitopic footprinting with a human monoclonal autoantibody locates a facet on the native antigen containing a highly conformational epitope.
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Autoimmune response to the thyroid in humans: thyroid peroxidase--the common autoantigenic denominator.
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Elephantiasic pretibial myxedema: insight into and a hypothesis regarding the pathogenesis of the extrathyroidal manifestations of Graves' disease.
Thyroid. 2000 Aug;10(8):685-92. doi: 10.1089/10507250050137761.
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Cellular thyroid peroxidase (TPO), unlike purified TPO and adjuvant, induces antibodies in mice that resemble autoantibodies in human autoimmune thyroid disease.
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