Lust G, Todhunter R J, Erb H N, Dykes N L, Williams A J, Burton-Wurster N I, Farese J P
James A. Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
J Am Vet Med Assoc. 2001 Nov 1;219(9):1242-6. doi: 10.2460/javma.2001.219.1242.
To compare the accuracy of the extended-hip radiographic (EHR) score, the distraction index (DI), and the dorsolateral subluxation (DLS) score for identifying hip dysplasia in dogs at 8 months of age.
Cohort study
129 Labrador Retrievers, Greyhounds, and Labrador Retriever-Greyhound crossbreds.
Radiography was performed when dogs were 8 months of age. Dogs were euthanatized at 8 to 36 months of age; hip dysplasia was diagnosed at the time of necropsy on the basis of results of a gross examination of the articular cartilage of the hip joints for signs of osteoarthritis.
The EHR score, DI, and DLS score at 8 months of age were all significantly correlated with degree of cartilage degeneration at necropsy. Sensitivity and specificity of using EHR score at 8 months of age to diagnose hip dysplasia (scores > 3 were considered abnormal) were 38 and 96%, respectively; sensitivity and specificity of using DI (values > 0.7 were considered abnormal) were 50 and 89%; and sensitivity and specificity of using DLS score (scores < 55% were considered abnormal) were 83 and 84%.
Results suggested that specificities of the 3 methods for diagnosing hip dysplasia in dogs at 8 months of age were similar. However, the DLS score had higher sensitivity, indicating that there were fewer false-negative results.
比较扩展髋关节X线摄影(EHR)评分、牵张指数(DI)和背外侧半脱位(DLS)评分在识别8月龄犬髋关节发育不良时的准确性。
队列研究
129只拉布拉多寻回犬、灵缇犬及拉布拉多寻回犬与灵缇犬的杂交犬。
犬8月龄时进行X线摄影。犬在8至36月龄时实施安乐死;根据髋关节关节软骨大体检查结果诊断骨关节炎迹象,在尸检时诊断髋关节发育不良。
8月龄时的EHR评分、DI和DLS评分均与尸检时软骨退变程度显著相关。8月龄时使用EHR评分诊断髋关节发育不良(评分>3视为异常)的敏感性和特异性分别为38%和96%;使用DI(值>0.7视为异常)的敏感性和特异性分别为50%和89%;使用DLS评分(评分<55%视为异常)的敏感性和特异性分别为83%和84%。
结果表明,这3种方法在诊断8月龄犬髋关节发育不良时的特异性相似。然而,DLS评分具有更高的敏感性,表明假阴性结果更少。