Emmrich P, Gauer J, Mättig H
Selbständige Abteilung für Neuropathologie, Universität Leipzig.
Zentralbl Chir. 2001 Sep;126(9):672-5. doi: 10.1055/s-2001-18242.
Two cases operated upon with the clinical diagnosis of unifocal autonomous functioning thyroid nodules (AFTN) are reported where the histological diagnosis revealed a well differentiated thyroid carcinoma (follicular, papillary) without metastasis. The pathogenesis of differentiated thyroid carcinomas in cases of AFTN may be coincident. Alternatively it may evolve from thyroid epithelial cells of the hot nodule, resulting in a "hot" well differentiated thyroid carcinoma. These cases show that under the clinical diagnosis of AFTN a differentiated thyroid carcinoma can be hidden occasionally.
报告了两例临床诊断为单灶自主性功能性甲状腺结节（AFTN）的手术病例，其组织学诊断显示为无转移的高分化甲状腺癌（滤泡性、乳头状）。AFTN病例中分化型甲状腺癌的发病机制可能是巧合。或者它可能从热结节的甲状腺上皮细胞演变而来，导致“热”的高分化甲状腺癌。这些病例表明，在AFTN的临床诊断下，偶尔可能隐藏着分化型甲状腺癌。
