Sivertsen A, Gravem P E, Johnsen S L, Magnussen I J, Søvik O
Plastikkirurgisk avdeling, Haukeland Sykehus 5021 Bergen.
Tidsskr Nor Laegeforen. 2001 Sep 30;121(23):2703-5.
Vaginal agenesia appears among 1 in 5,000-10,000 newborn girls, i.e. 3-6 patients per year in Norway.
From 1975 to 1998, 14 women (mean age 20 years) were operated for vaginal agenesia by McIndoe's method at Haukeland University Hospital. Twelve patients were examined 13 years later by questionnaire, gynaecological examination, ultrasound examination of the urinary tract, and blood and urinary test concerning kidney function and diabetes mellitus.
Five patients had been re-operated within nine months because of contracture. In all patients (except one), the constructed vagina had good elasticity, width and depth. The donor area at the medial thigh was unaesthetic in four patients. No abnormalities were found in the urinary tract by ultrasound. One patients had a familial syndrome with Müllerian aplasia, progressive renal disease and mild diabetes mellitus. All patients found the operation important, despite memories of a painful postoperative period.
This study shows functional and psychological satisfactory results of construction of vagina in women with vaginal agenesia.
阴道发育不全在每5000 - 10000名新生女婴中出现1例，即在挪威每年有3 - 6名患者。
1975年至1998年期间，14名女性（平均年龄20岁）在豪克兰大学医院接受了采用麦金杜法治疗阴道发育不全的手术。13年后，通过问卷调查、妇科检查、泌尿系统超声检查以及关于肾功能和糖尿病的血液及尿液检测对12名患者进行了检查。
5名患者因挛缩在9个月内再次接受手术。在所有患者（除1名患者外）中，再造阴道具有良好的弹性、宽度和深度。4名患者大腿内侧的供区不美观。超声检查未发现泌尿系统有异常。1名患者患有伴有苗勒管发育不全、进行性肾病和轻度糖尿病的家族综合征。尽管术后时期疼痛的记忆仍在，但所有患者都认为该手术很重要。
本研究表明阴道发育不全女性阴道再造在功能和心理方面都取得了令人满意的结果。
