甲状旁腺增生：新生儿高钙血症的罕见病因。

Parathyroid hyperplasia: an unusual cause of neonatal hypercalcemia.

作者信息

Payne M S, Suskind D L, Vargas A, Craver R, Liu D C

机构信息

Children's Hospital of New Orleans, LSU Health Sciences Center, Division of Otolaryngology, 200 Henry Clay Ave, New Orleans LA 70118, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2001 Dec 1;61(3):253-7. doi: 10.1016/s0165-5876(01)00560-2.

DOI:10.1016/s0165-5876(01)00560-2

PMID:11700196

Abstract

Primary hyperparathyroidism (PHPT) in infants is caused by parathyroid chief cell hyperplasia. Patients present with symptoms of chronic hypercalcemia, such as failure to thrive, irritability, abdominal pain, and anorexia. Medical therapy is inadequate, often resulting in chronic hypercalcemia or death. Partial or total surgical removal of the parathyroid gland is the preferred treatment. We describe a case of a 7-month-old infant with PHPT secondary to hyperplasia successfully treated with a subtotal parathyroidectomy.

摘要

婴儿原发性甲状旁腺功能亢进症（PHPT）由甲状旁腺主细胞增生引起。患者会出现慢性高钙血症的症状，如发育不良、易怒、腹痛和厌食。药物治疗效果不佳，常导致慢性高钙血症或死亡。甲状旁腺部分或全部手术切除是首选治疗方法。我们描述了一例7个月大的因增生继发PHPT的婴儿，通过甲状旁腺次全切除术成功治愈的病例。